With regard to Rouleaux, Fahraeus distinguished between healthy rouleaux and unhealthy - see his Suspension Stability in the Blood (https://journals.physiology.org/doi/epdf/10.1152/physrev.1929.9.2.241). A lot of attention was given to 'sludge' in the 1940s and 50s. It's related because when red blood cells clump together they sediment faster. At least one scientist (sorry haven't got the reference to hand) distinguished between aggregation, which he defined as reversible, and agglutination, which he defined as irreversible.
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Andrew Chapman wrote: Feb 24, 2023
Congratulations Health Minister!
With regard to Rouleaux, Fahraeus distinguished between healthy rouleaux and unhealthy - see his Suspension Stability in the Blood (https://journals.physiology.org/doi/epdf/10.1152/physrev.1929.9.2.241). A lot of attention was given to 'sludge' in the 1940s and 50s. It's related because when red blood cells clump together they sediment faster. At least one scientist (sorry haven't got the reference to hand) distinguished between aggregation, which he defined as reversible, and agglutination, which he defined as irreversible.